Search results for " GLP-1RA"

showing 3 items of 3 documents

The role of GLP-1 receptor agonists during COVID-19 pandemia: a hypothetical molecular mechanism

2021

ABSTRACT Introduction A number of anti-diabetic treatments have been favored during the continuing spread of the current SARS-CoV-2 pandemic. Glucagon like peptide-1 receptor agonists (GLP1-RAs) are a group of antidiabetic drugs, the glucose reducing effect of which is founded on augmenting glucose-dependent insulin secretion with concomitant reduction of glucagon secretion and delayed gastric emptying. Apart from their glucose lowering effects, GLP1-RAs also exert a plethora of pleiotropic activities in the form of anti-inflammatory, anti-thrombotic and anti-obesogenic properties, with beneficial cardiovascular and renal impact. All these make this class of drugs a preferred option for man…

Coronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)coronavirusSARS-COV-2PharmacologyIncretinsGlucagonGlucagon-Like Peptide-1 ReceptorAnimalsHumansHypoglycemic AgentsMedicinePharmacology (medical)ReceptorSpecial ReportGlucagon-like peptide 1 receptortherapyPandemicdiabetesSARS-CoV-2business.industrypandemicDiabetesCOVID-19General MedicineGLP-1RAcoronavirus diabetes GLP-1RA pandemic SARS-COV-2 therapy Animals COVID-19Diabetes Mellitus Type 2 Glucagon-Like Peptide-1 Receptor Humans Hypoglycemic Agents Incretins Signal Transduction Treatment OutcomeCOVID-19 Drug TreatmentCoronavirusTreatment OutcomeDiabetes Mellitus Type 2Molecular mechanismbusinessResearch ArticleSignal Transduction
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Adoption of the ADA/EASD guidelines in 10 Eastern and Southern European countries: Physician survey and good clinical practice recommendations from a…

2021

Aims: Evidence from cardiovascular outcomes trials (CVOTs) of glucagon-like peptide-1 receptor agonists and sodium-glucose cotransporter-2 inhibitors was reflected in the most recent guidelines from the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). The aim of the present study was to assess the adoption of the ADA/EASD guidelines in a convenience sample of physicians from Eastern and Southern Europe, the barriers to the implementation of these guidelines and the measures needed to facilitate their implementation. Methods: Attendees at two international diabetes conferences could volunteer to respond to a fully anonymous survey. Responses …

Malemedicine.medical_specialtyEndocrinology Diabetes and Metabolism030209 endocrinology & metabolismConvenience sampleSurvey resultGuidelines as Topic03 medical and health sciences0302 clinical medicineEndocrinologyPhysiciansSurveys and QuestionnairesInternal MedicineMedicineHumansAdherence Clinical guidelines GLP-1RAs SGLT2is Type 2 diabetes Europe Europe Eastern Female Guidelines as Topic Humans Male Physicians Surveys and Questionnaires030212 general & internal medicineEurope EasternReimbursementAmerican diabetes associationbusiness.industryGeneral Medicine3. Good healthEuropePublishingFamily medicinePhysician surveyGood clinical practiceFemalebusinessCardiovascular outcomesDiabetes research and clinical practice
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COVID-19 and diabetes management: What should be considered?

2020

medicine.medical_specialty2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Clinical effectivenessbusiness.industryEndocrinology Diabetes and MetabolismSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Cardiovascular disease COVID-19 Diabetes DPP4 GLP-1RA Hydroxychloroquine Pioglitazone SGLT-2General Medicinemedicine.diseaseEndocrinologyDiabetes managementDiabetes mellitusInternal MedicinemedicineSodium-Glucose Cotransporter 2 InhibitorIntensive care medicinebusinessPioglitazonemedicine.drugDiabetes research and clinical practice
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